{"id":372,"date":"2020-03-29T08:06:53","date_gmt":"2020-03-29T08:06:53","guid":{"rendered":"https:\/\/hanlab.me\/?page_id=372"},"modified":"2026-09-16T03:26:03","modified_gmt":"2026-09-16T03:26:03","slug":"publications","status":"publish","type":"page","link":"http:\/\/hanlab.me\/en\/publications\/","title":{"rendered":"PUBLICATION"},"content":{"rendered":"\n<div id=\"wp-block-themeisle-blocks-advanced-columns-0bd96338\" class=\"wp-block-themeisle-blocks-advanced-columns has-1-columns has-desktop-equal-layout has-tablet-equal-layout has-mobile-equal-layout has-vertical-unset has-default-gap\"><div class=\"wp-block-themeisle-blocks-advanced-columns-overlay\"><\/div><div class=\"innerblocks-wrap\">\n<div id=\"wp-block-themeisle-blocks-advanced-column-f4e811f4\" class=\"wp-block-themeisle-blocks-advanced-column\">\n<div class=\"wp-block-cover is-light\"><img decoding=\"async\" class=\"wp-block-cover__image-background wp-image-887 lazyload\" alt=\"\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools.png\" style=\"object-position:33% 49%\" data-object-fit=\"cover\" data-object-position=\"33% 49%\"\/><noscript><img decoding=\"async\" width=\"1200\" height=\"632\" class=\"wp-block-cover__image-background wp-image-887 lazyload\" alt=\"\" src=\"https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools.png\" style=\"object-position:33% 49%\" data-object-fit=\"cover\" data-object-position=\"33% 49%\" srcset=\"https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools.png 1200w, https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools-300x158.png 300w, https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools-1024x539.png 1024w, https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools-768x404.png 768w, https:\/\/hanlab.me\/wp-content\/uploads\/2023\/05\/online-publishing-tools-18x9.png 18w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><\/noscript><span aria-hidden=\"true\" class=\"wp-block-cover__background has-nv-c-1-background-color has-background-dim-0 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-large-font-size wp-block-paragraph\"><\/p>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center\"><\/h1>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:70%\">\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Liang, J.<sup>#<\/sup>, Yin, M.<sup>#<\/sup>, Su, Y., Zhang, L., <strong><strong><u>Han, Y<\/u><\/strong>.<\/strong>*,(2026) <a href=\"https:\/\/www.imrpress.com\/journal\/JIN\/25\/9\/10.31083\/JIN52398\" data-type=\"link\" data-id=\"https:\/\/www.imrpress.com\/journal\/JIN\/25\/9\/10.31083\/JIN52398\">Paraventricular Hypothalamic GLP-1R Neurons Mediate Propofol-Induced Suppression of Food Intake<\/a>. <strong><em>J Integr Neurosci.<\/em><\/strong> 25(9),\u00a052398 doi: 10.31083\/JIN52398.(<sup>#<\/sup>co-first author, *corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Zhang, X.<sup>#<\/sup>, Zhu, S.<sup>#<\/sup>, Lan, J., Duan, S., <strong><strong><u>Han, Y<\/u><\/strong>.<\/strong>*, Shi, P.*(2026) <a href=\"https:\/\/www.imrpress.com\/journal\/JIN\/25\/7\/10.31083\/JIN52117\" data-type=\"link\" data-id=\"https:\/\/www.imrpress.com\/journal\/JIN\/25\/7\/10.31083\/JIN52117\">Brain-Wide Connectivity of GLP1R Neurons in the Thalamic Reticular Nucleus<\/a>. <strong><em>J Integr Neurosci.<\/em><\/strong> 25(7):52117 doi: 10.31083\/JIN52117.(<sup>#<\/sup>co-first author, *corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Feng, X.<sup>#<\/sup>, Le, T.<sup>#<\/sup>, Liu, B., Zhao, H., Su, Y., Li, K., Shao, Y., Liu, J., Li, Z., Deng, G., Cao, K., Zhu, Z., Chen, J., Zeng, L., <strong><u>Han, Y<\/u><\/strong>., Yang, H., Yu, Y.-Q., Duan, S.*, Sun, L.*(2026) <a href=\"https:\/\/www.cell.com\/neuron\/abstract\/S0896-6273(26)00336-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627326003363%3Fshowall%3Dtrue\" data-type=\"link\" data-id=\"https:\/\/www.cell.com\/neuron\/abstract\/S0896-6273(26)00336-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627326003363%3Fshowall%3Dtrue\">low-wave sleep engages brainstem circuitry to prevent stress-induced anxiety<\/a>.<strong><em>Neuron.<\/em><\/strong> S0896-6273(26)00336-3. DOI:\u00a010.1016\/j.neuron.2026.04.041.(<sup>#<\/sup>co-first author, *corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Jian, Y.<sup>#<\/sup>, Jin, S.<sup>#<\/sup>, Liu, P.<sup>#<\/sup>, Zheng, X., Hong, X., <strong><u>Han, Y<\/u><\/strong>., Semyanov, A., Duan, S.*, Tong, X.*(2026) <a href=\"https:\/\/www.nature.com\/articles\/s41467-026-73488-0\" data-type=\"link\" data-id=\"https:\/\/www.nature.com\/articles\/s41467-026-73488-0\">GABA signaling in NG2 glia mediates empathy-like behavior under observational social defeat<\/a>.<strong><em>Nat Commun.<\/em><\/strong> 17(1):6812. DOI:\u00a010.1038\/s41467-026-73488-0.(<sup>#<\/sup>co-first author,*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Wang,M., <strong><u>Han, Y.<\/u><\/strong>, Zhang, C.* (2024) <a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13046-024-03205-6\" data-type=\"link\" data-id=\"https:\/\/elifesciences.org\/articles\/82649\">Noval insights and therapeutic strategies for tumor-induced kidney pathologies<\/a>. <strong><em>J Exp Clin Cancer Res<\/em><\/strong>. doi: 10.1186\/s13046-024-03205-6.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, Xia, G., Harris, L., Liu, P., Guan, D., Wu, Q.* (2024) <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.04.30.591948v1\" data-type=\"link\" data-id=\"https:\/\/elifesciences.org\/articles\/82649\">Reversal of Obesity by Enhancing Slow-wave Sleep via a Prokineticin Receptor Neural Circuit<\/a>. <strong><em>bioRxiv <\/em><\/strong>[Preprint]. doi: https:\/\/doi.org\/10.1101\/2024.04.30.591948.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, He, Y., Harris, L., Xu, Y., Wu, Q.* (2023) <a href=\"https:\/\/elifesciences.org\/articles\/82649\" data-type=\"link\" data-id=\"https:\/\/elifesciences.org\/articles\/82649\">Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity<\/a>. <strong><em>eLife<\/em><\/strong>. doi: https:\/\/doi.org\/10.7554\/eLife.82649.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Wang, F., Chen, Y., Lin, Y., Wang, X., Li, K., <strong><u>Han, Y<\/u><\/strong>., Wu, J., Shi, X., Zhu, Z., Long, C., \u00a0Hu, X., Duan, S.*, Gao, Z.*\u00a0(2023) <a href=\"https:\/\/elifesciences.org\/articles\/85450\" data-type=\"URL\" data-id=\"https:\/\/elifesciences.org\/articles\/85450\">A parabrachial to hypothalamic pathway mediates defensive behavior<\/a>. <strong><em>eLife<\/em><\/strong>. doi: https:\/\/doi.org\/10.7554\/eLife.85450.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Hong, S., Kim, W.,<strong><u>Han, Y.<\/u><\/strong>, Cherukuri, R., Jung, H., Campos, C., Wu, Q., Park, S.* (2022) <a href=\"https:\/\/bio-protocol.org\/pdf\/Bio-protocol4341.pdf\" data-type=\"URL\" data-id=\"https:\/\/bio-protocol.org\/pdf\/Bio-protocol4341.pdf\">Optogenetic Targeting of Mouse Vagal Afferents Using an Organ-specific, Scalable, Wireless Optoelectronic Device<\/a>. <strong><em>Bio Protoc<\/em><\/strong>. 12(5):e4341.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, Xia, G., He, Y., Farias, M., Xu, Y., Wu, Q.*(2021) <a href=\"https:\/\/www.science.org\/doi\/full\/10.1126\/sciadv.abf8719\" data-type=\"URL\" data-id=\"https:\/\/www.science.org\/doi\/full\/10.1126\/sciadv.abf8719\">A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation<\/a>. <strong><em>Sci. Adv<\/em><\/strong>. 7(22):eabf8719.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y<\/u><\/strong><sup>#<\/sup><strong><u>.<\/u><\/strong>, Xia, G<sup>#<\/sup>., Srisai, D<sup>#<\/sup>., Meng, F., He, Y., Ran, Y., Farias, M., Hoang, G., Toth, I., Dietrich, M., Chen, MH., Xu, Y., Wu, Q.* (2021) <a href=\"https:\/\/www.nature.com\/articles\/s41467-021-23846-x\" data-type=\"URL\" data-id=\"https:\/\/www.nature.com\/articles\/s41467-021-23846-x\">Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding<\/a>. <strong><em>Nat Commun.<\/em><\/strong> 12(1):3525. (<sup>#<\/sup>co-first author,*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Xia, G<sup>#<\/sup>., <strong><u>Han, Y<\/u><\/strong><sup>#<\/sup><strong>.<\/strong>, Meng, F., He, Y., Srisai, D., Farias, M., Dang, M., Xu, Y., Palmiter, RD., Wu, Q.* (2021) <a href=\"https:\/\/www.nature.com\/articles\/s41380-021-01053-w\" data-type=\"URL\" data-id=\"https:\/\/www.nature.com\/articles\/s41380-021-01053-w\">Reciprocal control of obesity and anxiety\u2013depressive disorder via a GABA and serotonin neural circuit<\/a>. <strong><em>Mol. Psychiatry.<\/em><\/strong> doi: 10.1038\/s41380-021-01053-w. (<sup>#<\/sup>co-first author, *corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Lu, Y., Zhu, Z., Ma, Q., Su, Y., <strong><u>Han, Y.<\/u><\/strong>, Wang, X., Duan, S.*, Yu, Y.* (2018) <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s12264-018-0303-x\" data-type=\"URL\" data-id=\"https:\/\/link.springer.com\/article\/10.1007\/s12264-018-0303-x\">A critical time-window for the selective induction of hippocampal memory consolidation by a brief episode of slow-wave sleep<\/a>. <strong><em>Neurosci. Bull.<\/em><\/strong> 34(6):1091-1099.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Meng, F., <strong><u>Han, Y.<\/u><\/strong>, Srisai, D., Belakhov, V., Farias, M., Xu, Y., Palmiter, R.D., Baasov, T. &amp; Wu, Q.*(2016) <a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.1602049113\" data-type=\"URL\" data-id=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.1602049113\">A new inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism<\/a>. <strong><em>Proc. Natl. Acad. Sci. U.S.A.<\/em><\/strong> 113:3645\u20133650.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Wang, M., Zuris, J.A., Meng, F., Rees, H., Deng, P., <strong><u>Han, Y.<\/u><\/strong>, Gao, X., Pouli, D., Wu, Q., Georgakoudi, I., Liu, D.R. &amp; Xu, Q.* (2016) <a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.1520244113\" data-type=\"URL\" data-id=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.1520244113\">Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles<\/a>. <strong><em>Proc. Natl. Acad. Sci. U.S.A.<\/em><\/strong> 113:2868-73.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, Huang, M., Sun, M., Duan, S.&amp; Yu, Y.* (2015) <a href=\"https:\/\/academic.oup.com\/cercor\/article\/25\/9\/2741\/2926084\" data-type=\"URL\" data-id=\"https:\/\/academic.oup.com\/cercor\/article\/25\/9\/2741\/2926084\">Long-term synaptic plasticity in rat barrel cortex<\/a>. <strong><em>Cereb. Cortex.<\/em><\/strong> 25(9):2741-51.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Shi, Y., <strong><u>Han, Y.<\/u><\/strong>, Su, Y., Yang, J., Yu, Y.* (2015) <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0130130\" data-type=\"URL\" data-id=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0130130\">Silencing of cholinergic basal forebrain neurons using archaerhodopsin prolongs slow-wave sleep in mice<\/a>. <strong><em>PLoS ONE.<\/em><\/strong> 10(7): e0130130.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Zhou, R., Lu, Y., <strong><u>Han, Y.<\/u><\/strong>, Li, X., Lou, H., Zhu, L., Zhen, X., Duan, S.* (2015) <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0278584615001347?via%3Dihub\" data-type=\"URL\" data-id=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0278584615001347?via%3Dihub\">Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression<\/a>. <strong><em>Prog. Neuropsychopharmacol. Biol. Psychiatry. <\/em><\/strong>63:110-118.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, Shi, Y., Xi, W., Zhou, R., Tan, Z., Wang, H., Li, X., Chen, Z., Feng, G., Luo, M., Huang, Z., Duan, S.* &amp; Yu, Y.* (2014) <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960982214001493\" data-type=\"URL\" data-id=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960982214001493\">Selective activation of cholinergic basal forebrain neurons induces immediate sleep-wake transitions<\/a>. <strong><em>Curr. Biol.<\/em><\/strong> 24: 693-698.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, Yu, H., Sun, M., Wang, Y., Xi, W., Yu, Y.*(2014) <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/ejn.12394\" data-type=\"URL\" data-id=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/ejn.12394\">Astrocyte-restricted disruption of connexin-43 impairs neuronal plasticity in mouse barrel cortex<\/a>. <strong><em>Eur. J. Neurosci.<\/em><\/strong> 39: 35-45.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Sun, M., Yu, H., <strong><u>Han, Y.<\/u><\/strong>, Tian, J., Yu, Y.* (2013) <a href=\"https:\/\/www.cps.org.tw\/issues\/file\/201412192134370.pdf\" data-type=\"URL\" data-id=\"https:\/\/www.cps.org.tw\/issues\/file\/201412192134370.pdf\">Glial modulation of vibrissal sensory processing in rats<\/a>. <strong><em>Chin. J. Physiol.<\/em><\/strong> 56: 309-317.(*corresponding author)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>BOOK CHAPTER<\/u><\/strong><strong><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><strong><u>Han, Y.<\/u><\/strong>, Xia, G. &amp;Wu, Q. (2018) <a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-981-13-1286-1_1\" data-type=\"URL\" data-id=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-981-13-1286-1_1\">Functional interrogation of the AgRP neural circuits in control of appetite, body weight, and behaviors<\/a>. <strong><em>Adv. Exp. Med. Biol. <\/em><\/strong>1090:1-16.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Wu, Q., <strong><u>Han, Y.<\/u><\/strong> &amp; Tong, Q. (2018) <a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-981-13-1286-1_12\" data-type=\"URL\" data-id=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-981-13-1286-1_12\">Current genetic techniques in neural circuit control of feeding and energy metabolism<\/a>. <strong><em>Adv. Exp. Med. Biol. <\/em><\/strong>1090:211-233.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:18px\">Pubmed\u5b8c\u6574\u6587\u7ae0\u5217\u8868\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/yong.han.4\/bibliography\/public\/\">https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/yong.han.4\/bibliography\/public\/<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Liang, J.#, Yin, M.#, Su, Y., Zhang, L., Han, Y.*,(2026&hellip;&nbsp;<a href=\"http:\/\/hanlab.me\/en\/publications\/\" rel=\"bookmark\">Read More &raquo;<span class=\"screen-reader-text\">PUBLICATION<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/template-pagebuilder-full-width.php","meta":{"neve_meta_sidebar":"full-width","neve_meta_container":"","neve_meta_enable_content_width":"on","neve_meta_content_width":80,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-372","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/pages\/372","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/comments?post=372"}],"version-history":[{"count":36,"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/pages\/372\/revisions"}],"predecessor-version":[{"id":1492,"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/pages\/372\/revisions\/1492"}],"wp:attachment":[{"href":"http:\/\/hanlab.me\/en\/wp-json\/wp\/v2\/media?parent=372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}